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NIAMS scientists find potential new way to block inflammation in autoimmune disease
on 19. Jun 2008 in Arthritis, Gout, & Joint Disease, Arthritis, Gout, & Joint Disease.

Researchers from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health (NIH), have identified a promising new target for autoimmune disease treatment – a cell-surface receptor called DR3. Their research in mice, published on …
Joint distraction promotes structural repair in patients with severe knee osteoarthritis
on 14. Jun 2008 in Arthritis, Gout, & Joint Disease, Arthritis, Gout, & Joint Disease.

Almost complete normalization achieved within 6 months and sustained up to 2 years later

Joint distraction (the use of a surgical frame around a degenerated joint to strengthen and promote repair) promotes cartilage repair in severe end stage osteoarthritis (OA) of the knee, as demonstrated for t…
Biogen Idec’s baminercept alfa shows promise in patients with rheumatoid arthritis
on 12. Jun 2008 in Arthritis, Gout, & Joint Disease, Arthritis, Gout, & Joint Disease.

Investigational compound designed to disrupt autoimmune cascade

Biogen Idec will present data on baminercept alfa (BG9924, LTßR-Ig), the first dual-mechanism, lymphotoxin-ß; (LT-ß;) and LIGHT pathway inhibitor in development for the treatment of autoimmune diseases, including rheumatoid arthri…
A New Approach to Treating Autoimmune Disease
on 02. Jun 2008 in Gastrointestinal IBD, Gastrointestinal - IBD, Arthritis, Gout, & Joint Disease, Arthritis, Gout, & Joint Disease.

In autoimmune diseases, the immune system turns against the body’s own tissues and organs, wreaking havoc and destruction for no apparent reason. Partly because the origins of these diseases are so obscure, no effective treatment exists, and the suffering they inflict is enormous. Now Weizmann Ins…

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The HLA-DRB1 gene and premature death in rheumatoid arthritis
on 31. Jan 2008 in Arthritis, Gout, & Joint Disease, Arthritis, Gout, & Joint Disease.

Gene linked to increased risk of developing inflammatory arthritis may also increase patients’ risk of dying from cardiovascular disease
People with rheumatoid arthritis (RA), an inflammatory autoimmune disease, tend to die younger and, largely from cardiovascular disease (CVD). One explanation for…
A major step toward a more targeted treatment for auto-immune diseases?
on 28. Jan 2008 in Gastrointestinal - IBD, Gastrointestinal IBD, Fibromyalgia & Chronic Fatigue Syndrome, Fibromyalgia & Chronic Fatigue Syndrome, Arthritis, Gout, & Joint Disease, Arthritis, Gout, & Joint Disease.

More and more people in Western society are suffering from auto-immune diseases. Discovering the cause of these chronic inflammations is a first important step in the search for targeted medicines. VIB researchers connected to Ghent University and the Katholieke Universiteit Leuven joined forces and…

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Study suggests genetic connection between short stature and arthritis
on 14. Jan 2008 in Arthritis, Gout, & Joint Disease, Arthritis, Gout, & Joint Disease.

Common genetic variants linked to arthritis may also play a role in human height, a new study shows.

The international study was co-led by the University of Michigan School of Public Health. The journal Nature Genetics will publish the findings online Jan. 13.

The new study confirms observati…
Exercise program improves symptoms in arthritis patients
on 04. Jan 2008 in Arthritis, Gout, & Joint Disease, Arthritis, Gout, & Joint Disease.

Patients with arthritis, the country’s leading cause of disability, tend to be less fit than their peers who don’t have this condition. Studies have shown, however, that they can safely participate in exercise programs to increase their fitness, strength and psychosocial status and that health p…
Antibody responses in patients with Lyme arthritis
on 29. Nov 2007 in Arthritis, Gout, & Joint Disease, Arthritis, Gout, & Joint Disease.

Study sheds light on antibiotic resistance and persistent joint inflammation

Lyme disease in the U.S. is caused by a form of bacteria, the spirochete Borrelia burgdorferi, infecting humans by tick bites. It typically begins with a bull’s-eye skin rash, accompanied by fever, muscle aches, or oth…